LANDAU-KLEFFNER SYNDROME: A SYSTEMATIC REVIEW AND TWO ILLUSTRATIVE CASES

Abstract

 INTRODUCTION: This study analyzes the treatments available for Landau Kleffner Syndrome (LKS) and evaluates its potential benefits, comparing the literature with two cases of patients diagnosed with LKS treated surgically by the technique adapted from the multiple subpial  transection (MST).

METHODS: A review was conducted on the PUBMED. The selected articles were those that had "DOI" or if not have “DOI”, the article contained in the summary information about the patient. 113 articles were selected and organized for statistical analysis.

RESULTS: Male patients are most affected. The probability of having a total regression is more likely in surgical treatment. The MST is indicated in the cases reported due to the need for surgical resection of the affected areas to ensure the maintenance of eloquent brain functions.

CONCLUSION: MST presents significant improvement results in epilepsy and aphasia of patients, showing to be an important technique in the treatment of LKS.